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Development of a plasma-activated indwelling device for improved ctDNA capture

By Dr Judy Ann Cocadiz

We are pleased to announce the recipients of the National Research Grant Round 2025.

Dr Judy Ann Cocadiz

Read about Dr Judy Ann Cocadiz, one of our grant recipients.

Dr Judy Ann Cocadiz 

University of Otago 

Post-Doctoral Fellowship - $300,000 over 3 years 

Development of a plasma-activated indwelling device for improved ctDNA capture 

This research will develop the core component for a small device that can capture tiny pieces of genetic material, called circulating tumour DNA (ctDNA), which are released into the bloodstream by cancer cells. This device is designed to be temporarily inserted into a blood vessel for a short period (~30mins), allowing it to directly collect ctDNA, which can then be analysed for signs of cancer. This technology could help doctors detect cancers, even in early stages, and monitor for any remaining or recurring cancer after treatment without needing to take blood samples. It could be particularly useful for detecting cancer in children, where only small blood samples can be taken. The device’s surface is treated to improve its ability to capture ctDNA more effectively. This innovation could lead to earlier and more accurate cancer diagnosis and monitoring, making it a powerful tool for improving cancer care and patient outcomes.